Debutant Aamer Jamal was handed the responsibility to defend 15 in the last over and he did so against the dangerous Moeen Ali.
Resultantly, the hosts have taken a 3-2 lead in the seven-match series.
In the first innings, England fast bowler Mark Wood’s express pace helped the tourists bowl out Pakistan for a below-par 145 in the fifth T20 international in Lahore on Wednesday.
Wood — playing only his second international since undergoing elbow surgery — took 3-20 after the home team were sent in to bat at Gaddafi Stadium.
Wood’s fellow pacers Sam Curran (2-23) and David Willey (2-23) also bowled with hostility as Pakistan were dismissed in 19 overs.